{"id":2992,"date":"2024-11-20T23:49:55","date_gmt":"2024-11-20T23:49:55","guid":{"rendered":"https:\/\/kamranaghayev.com\/dish-hastaligi\/"},"modified":"2026-11-04T20:05:46","modified_gmt":"2026-11-04T20:05:46","slug":"dish-hastaligi","status":"publish","type":"post","link":"https:\/\/kamranaghayev.com\/tr\/dish-hastaligi\/","title":{"rendered":"DISH Hastal\u0131\u011f\u0131: Belirtileri, Tan\u0131s\u0131 ve Ne Anlama Geldi\u011fi"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>DISH, yani diff\u00fcz idiopatik iskelet hiperostozu, ba\u011flar\u0131n ve tendonlar\u0131n iskelete yap\u0131\u015ft\u0131\u011f\u0131 yerlerde kemik olu\u015fmas\u0131d\u0131r.<\/strong> Forestier hastal\u0131\u011f\u0131 olarak da bilinir. Omurgada fazladan kemik genellikle omurlar\u0131n \u00f6n ve yan y\u00fcz\u00fc boyunca b\u00fcy\u00fcr ve birka\u00e7 omuru tek bir sert b\u00f6l\u00fcm h\u00e2linde birle\u015ftirebilir. Baz\u0131 ki\u015filerde hi\u00e7 \u015fik\u00e2yet olmaz ve DISH ba\u015fka bir nedenle \u00e7ekilen bir g\u00f6r\u00fcnt\u00fcde fark edilir; baz\u0131lar\u0131nda ise a\u011fr\u0131, tutukluk ya da daha seyrek olarak tedavi gerektiren bir komplikasyon g\u00f6r\u00fcl\u00fcr.<sup><a href=\"#ref-o1\">1<\/a>, <a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">DISH tan\u0131n\u0131z varsa ve neyin yard\u0131mc\u0131 olabilece\u011fini \u00f6\u011frenmek istiyorsan\u0131z, <a href=\"https:\/\/kamranaghayev.com\/tr\/dish-hastaligi-tedavisi\/\">DISH hastal\u0131\u011f\u0131 tedavisi ve ameliyat\u0131n ne zaman yard\u0131mc\u0131 olabilece\u011fi<\/a> yaz\u0131s\u0131n\u0131 okuyun.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Bu yaz\u0131da:<\/strong> <a href=\"#h-what-is-dish-disease\">DISH nedir<\/a> \u00b7 <a href=\"#h-dish-disease-symptoms\">Belirtiler<\/a> \u00b7 <a href=\"#h-dish-diagnosis-and-tests\">Tan\u0131 ve g\u00f6r\u00fcnt\u00fcleme<\/a> \u00b7 <a href=\"#h-spinal-segments-affected-by-dish\">Omurgan\u0131n hangi b\u00f6l\u00fcmlerini etkiler<\/a> \u00b7 <a href=\"#h-dish-and-related-conditions\">DISH mi, ankilozan spondilit mi?<\/a> \u00b7 <a href=\"#h-diffuse-idiopathic-skeletal-hyperostosis-causes\">Nedenleri<\/a> \u00b7 <a href=\"#h-dish-prognosis\">Seyir ve tedavi<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-dish-disease\">DISH nedir?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ba\u011flar\u0131n, tendonlar\u0131n ve eklem kaps\u00fcllerinin kemi\u011fe yap\u0131\u015ft\u0131\u011f\u0131 yerlere entezis denir. DISH&#8217;te bu b\u00f6lgelerde kalsiyum birikir ve zamanla kemik olu\u015fur. Omurga boyunca bu s\u00fcre\u00e7 \u00e7o\u011funlukla omur g\u00f6vdelerinin \u00f6n\u00fcnden inen bant olan \u00f6n longitudinal ba\u011f\u0131 izler.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kemikten \u00e7\u0131kan uzant\u0131ya osteofit ya da kemik \u00e7\u0131k\u0131nt\u0131s\u0131 denir. DISH&#8217;te baz\u0131 osteofitler ayr\u0131 kal\u0131r; baz\u0131lar\u0131 birbirine do\u011fru b\u00fcy\u00fcyerek kom\u015fu omurlar aras\u0131nda k\u00f6pr\u00fc kurar ve omurgan\u0131n o b\u00f6l\u00fcm\u00fcn\u00fc sertle\u015ftirir. G\u00f6r\u00fcnt\u00fcdeki kemik miktar\u0131 \u015fik\u00e2yetleri pek iyi \u00f6ng\u00f6rmez. Yayg\u0131n k\u00f6pr\u00fcler az sorun yaratabilirken, \u00f6nemli bir yap\u0131n\u0131n yan\u0131ndaki daha k\u00fc\u00e7\u00fck bir \u00e7\u0131k\u0131nt\u0131 dikkatli bir de\u011ferlendirme gerektirebilir.<sup><a href=\"#ref-o1\">1<\/a>, <a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;\u0130diopatik&#8221; nedenin bilinmedi\u011fi anlam\u0131na gelir. &#8220;Diff\u00fcz&#8221; ve &#8220;iskelet&#8221; s\u00f6zc\u00fckleri, DISH&#8217;in yaln\u0131zca omurgay\u0131 de\u011fil le\u011fen kemi\u011fi ve kollarla bacaklardaki yap\u0131\u015fma yerlerini de etkileyebilece\u011fini anlat\u0131r. DISH ya\u015fla birlikte daha s\u0131k g\u00f6r\u00fcl\u00fcr ve erkeklerde daha yayg\u0131nd\u0131r. Bildirilen s\u0131kl\u0131klar toplulu\u011fa ve kullan\u0131lan \u00f6l\u00e7\u00fctlere g\u00f6re b\u00fcy\u00fck farkl\u0131l\u0131k g\u00f6sterir.<sup><a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-forestiers-disease-another-medical-term-for-dish\">Forestier hastal\u0131\u011f\u0131 ile DISH ayn\u0131 \u015fey mi?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Evet. Jacques Forestier ve Jaume Rot\u00e9s-Querol bu durumu 1950&#8217;de &#8220;omurgan\u0131n senil ankilozan hiperostozu&#8221; olarak tan\u0131mlad\u0131 ve Forestier hastal\u0131\u011f\u0131 ad\u0131 h\u00e2l\u00e2 yayg\u0131n olarak kullan\u0131l\u0131yor. Ankilozan hiperostoz ayn\u0131 anlama gelen daha eski bir terimdir. DISH ad\u0131 daha sonra, durumun omurga d\u0131\u015f\u0131ndaki iskeleti de etkileyebilece\u011fi anla\u015f\u0131l\u0131nca ortaya \u00e7\u0131kt\u0131.<sup><a href=\"#ref-o3\">3<\/a>, <a href=\"#ref-o14\">4<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dish-disease-symptoms\">Belirtiler ve ne zaman doktora ba\u015fvurmal\u0131<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Belirtiler, kemi\u011fin nerede olu\u015ftu\u011funa ve omurgada ba\u015fka neler oldu\u011funa ba\u011fl\u0131d\u0131r. En s\u0131k g\u00f6r\u00fclenler \u015funlard\u0131r:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u00e7o\u011funlukla s\u0131rt\u0131n ortas\u0131nda, d\u00f6nmeyi ve e\u011filmeyi zorla\u015ft\u0131ran tutukluk;<\/li>\n\n\n\n<li>omurgan\u0131n \u00fczerinde ya da hemen yan\u0131nda a\u011fr\u0131;<\/li>\n\n\n\n<li>omurga d\u0131\u015f\u0131ndaki tendon yap\u0131\u015fma yerlerinde, \u00f6rne\u011fin topukta ya da dirsekte a\u011fr\u0131.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">DISH y\u0131llar i\u00e7inde geli\u015fti\u011fi i\u00e7in tutuklu\u011fu ya\u015fa ba\u011flamak kolayd\u0131r. DISH&#8217;li ki\u015fileri, aksiyel spondiloartriti olanlar\u0131 ve sa\u011fl\u0131kl\u0131 g\u00f6n\u00fcll\u00fcleri kar\u015f\u0131la\u015ft\u0131ran bir ara\u015ft\u0131rmada DISH grubunda omurga hareketlili\u011fi ve fiziksel performans\u0131n belirgin bi\u00e7imde azald\u0131\u011f\u0131, bu azalman\u0131n spondiloartrit grubuna benzer d\u00fczeyde oldu\u011fu g\u00f6r\u00fcld\u00fc. DISH yaln\u0131zca g\u00f6r\u00fcnt\u00fcdeki bir bulgu de\u011fildir.<sup><a href=\"#ref-o4\">5<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Baz\u0131 ki\u015filerde kemi\u011fin yak\u0131ndaki bir yap\u0131ya bask\u0131 yapmas\u0131 ya da omurgada e\u015flik eden bir sorun nedeniyle komplikasyon geli\u015fir. Ayn\u0131 belirtilere ba\u015fka hastal\u0131klar da yol a\u00e7abilece\u011fi i\u00e7in bunlar\u0131n ayr\u0131ca de\u011ferlendirilmesi gerekir:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>Belirti<\/th><th>Neyin kontrol edilmesi gerekebilir<\/th><\/tr><\/thead><tbody><tr><td>Yutma g\u00fc\u00e7l\u00fc\u011f\u00fc, seste de\u011fi\u015fiklik ya da h\u0131r\u0131lt\u0131l\u0131 solunum<\/td><td>Yutak ve yemek borusu yak\u0131n\u0131ndaki b\u00fcy\u00fck boyun osteofitleri ve di\u011fer nedenler<\/td><\/tr><tr><td>G\u00fc\u00e7s\u00fczl\u00fck, uyu\u015fma, beceriksizlik ya da dengesiz y\u00fcr\u00fcme<\/td><td>\u00c7o\u011funlukla e\u015flik eden dejenerasyona ba\u011fl\u0131 omurilik ya da sinir bas\u0131s\u0131<\/td><\/tr><tr><td>D\u00fc\u015fme ya da hafif bir darbe sonras\u0131 boyunda veya s\u0131rtta yeni a\u011fr\u0131<\/td><td>Sert b\u00f6l\u00fcmden ge\u00e7en bir k\u0131r\u0131k<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Kaynaklar: klinik derleme,<sup><a href=\"#ref-o2\">2<\/a><\/sup> boyunla ilgili derleme,<sup><a href=\"#ref-o5\">6<\/a><\/sup> k\u0131r\u0131k \u00f6nerileri.<sup><a href=\"#ref-o6\">7<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Bir yaralanma sonras\u0131 yeni ve \u015fiddetli a\u011fr\u0131, yeni g\u00fc\u00e7s\u00fczl\u00fck ya da y\u00fcr\u00fcyememe, aniden ba\u015flayan nefes alma veya yutma g\u00fc\u00e7l\u00fc\u011f\u00fc varsa acil yard\u0131m al\u0131n.<\/strong> Ekibe DISH&#8217;iniz oldu\u011funu s\u00f6yleyin: kayna\u015fm\u0131\u015f bir omurgadaki k\u0131r\u0131k dengesiz olabilir ve d\u00fcz r\u00f6ntgende kolayca g\u00f6zden ka\u00e7abilir.<sup><a href=\"#ref-o6\">7<\/a><\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-how-serious-is-dish-disease\">DISH ne kadar ciddidir?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ayn\u0131 tan\u0131 \u00e7ok farkl\u0131 durumlar\u0131 kapsar. DISH&#8217;i g\u00f6\u011f\u00fcs BT&#8217;sinde tesad\u00fcfen fark edilen biriyle yutma g\u00fc\u00e7l\u00fc\u011f\u00fc, omurilik bas\u0131s\u0131 ya da k\u0131r\u0131\u011f\u0131 olan birinin ihtiya\u00e7lar\u0131 farkl\u0131d\u0131r. \u00c7o\u011fu ki\u015fi bir komplikasyonla de\u011fil, tutukluk ve bir miktar a\u011fr\u0131yla ya\u015far. \u015eik\u00e2yetler ortaya \u00e7\u0131kt\u0131\u011f\u0131nda iyi bir de\u011ferlendirme, bunlar\u0131n g\u00f6r\u00fcnt\u00fcdeki bulguyla uyu\u015fup uyu\u015fmad\u0131\u011f\u0131n\u0131 ve ba\u015fka bir nedenin sorumlu olup olmad\u0131\u011f\u0131n\u0131 sorgular.<sup><a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dish-diagnosis-and-tests\">DISH tan\u0131s\u0131 nas\u0131l konur?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Tan\u0131; \u00f6yk\u00fc, muayene ve g\u00f6r\u00fcnt\u00fclemenin bir araya getirilmesiyle konur. DISH&#8217;i genellikle g\u00f6r\u00fcnt\u00fclerdeki tablo ortaya koyar. \u00d6yk\u00fc ve muayene ise \u015fik\u00e2yetleri DISH&#8217;in mi a\u00e7\u0131klad\u0131\u011f\u0131n\u0131, yoksa dejenerasyonun, bir eklem sorununun ya da ba\u015fka bir hastal\u0131\u011f\u0131n m\u0131 i\u015fin i\u00e7inde oldu\u011funu g\u00f6sterir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Klasik Resnick\u2013Niwayama \u00f6l\u00e7\u00fctleri; en az d\u00f6rt kom\u015fu omurun \u00f6n ve yan y\u00fcz\u00fc boyunca akan bir kemik olu\u015fumunu, disk y\u00fcksekliklerinin g\u00f6rece korunmas\u0131n\u0131 ve ankilozan spondilite \u00f6zg\u00fc sakroiliak eklem erozyonu ya da kayna\u015fmas\u0131 ile faset eklem kayna\u015fmas\u0131n\u0131n bulunmamas\u0131n\u0131 tarif eder.<sup><a href=\"#ref-o1\">1<\/a><\/sup> Bu \u00f6l\u00e7\u00fctler h\u00e2l\u00e2 ba\u015fvuru noktas\u0131d\u0131r, ama s\u0131n\u0131rlar\u0131 vard\u0131r. BT \u00e7al\u0131\u015fmalar\u0131 DISH&#8217;li ki\u015filerin bir b\u00f6l\u00fcm\u00fcnde sakroiliak eklemler \u00e7evresinde k\u0131smi k\u00f6pr\u00fcle\u015fme ya da kayna\u015fma oldu\u011funu g\u00f6steriyor; yani tek bir bulgu her durumda tan\u0131y\u0131 belirlemez. BT&#8217;ye dayanan daha yeni \u00f6l\u00e7\u00fctler de \u00f6nerilmi\u015ftir.<sup><a href=\"#ref-o7\">8<\/a>, <a href=\"#ref-o8\">9<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bir g\u00f6r\u00fcnt\u00fc DISH&#8217;i a\u00e7\u0131k\u00e7a g\u00f6sterip yine de belirli bir a\u011fr\u0131y\u0131 a\u00e7\u0131klamayabilir. Bu ba\u011flant\u0131 \u00f6yk\u00fc ve muayeneyle kurulur.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-x-ray\">R\u00f6ntgen<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Omurga r\u00f6ntgeni omurlar\u0131n \u00f6n\u00fc boyunca akan kemi\u011fi, aralar\u0131ndaki k\u00f6pr\u00fcleri ve omurgan\u0131n genel duru\u015funu g\u00f6sterebilir. DISH \u00e7o\u011fu zaman ilk kez r\u00f6ntgende fark edilir. \u00dc\u00e7 boyutlu omurgay\u0131 d\u00fcz bir g\u00f6r\u00fcnt\u00fcye s\u0131k\u0131\u015ft\u0131rd\u0131\u011f\u0131 i\u00e7in baz\u0131 seviyeleri ve kemi\u011fin yak\u0131n yap\u0131larla ili\u015fkisini g\u00f6rmek zor olabilir.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/04\/DISH-Xray.webp\" alt=\"Boynun yandan r\u00f6ntgeni: DISH'te birka\u00e7 boyun omurunun \u00f6n\u00fc boyunca inen kal\u0131n kemik\" class=\"wp-image-5253\"\/><figcaption class=\"wp-element-caption\">Boyun omurgas\u0131n\u0131n yandan g\u00f6r\u00fcn\u00fcm\u00fc: omurlar\u0131n \u00f6n\u00fc boyunca akan, boyundaki DISH&#8217;e \u00f6zg\u00fc kemik. G\u00f6rsel kayna\u011f\u0131: www.orthobullets.com.<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-computerized-tomography-ct-scan\">BT (bilgisayarl\u0131 tomografi)<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">BT omurgay\u0131 kesit kesit g\u00f6r\u00fcnt\u00fcler. Kesitler her d\u00fczlemde incelenebilir ya da her osteofitin tam boyutunu, \u015feklini ve yerini g\u00f6steren \u00fc\u00e7 boyutlu bir g\u00f6r\u00fcnt\u00fcde birle\u015ftirilebilir. Bu, doktorun kemi\u011fin yemek borusuna, bir sinire ya da bir damara ne kadar yak\u0131n oldu\u011funu bilmesi gerekti\u011finde \u00f6nemlidir.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/05\/Figure-1-1-e1741017890838.jpg\" alt=\"Torakal omurgan\u0131n \u00fc\u00e7 boyutlu BT g\u00f6r\u00fcnt\u00fcs\u00fc: sa\u011f \u00f6n y\u00fcz boyunca yo\u011fun, akan osteofitler\" class=\"wp-image-5586\" style=\"width:597px;height:auto\"\/><figcaption class=\"wp-element-caption\">DISH&#8217;te torakal omurgan\u0131n \u00fc\u00e7 boyutlu BT g\u00f6r\u00fcnt\u00fcs\u00fc. Yo\u011fun ve akan osteofitler omurlar\u0131n sa\u011f \u00f6n y\u00fcz\u00fc boyunca uzan\u0131yor.<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-mr-ve-di-er-tetkikler\">MR ve di\u011fer tetkikler<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MR omurili\u011fi, sinirleri ve yumu\u015fak dokular\u0131 g\u00f6sterir. DISH&#8217;in kendisinin tan\u0131s\u0131 i\u00e7in de\u011fil, n\u00f6rolojik \u015fik\u00e2yetler ya da olas\u0131 bir k\u0131r\u0131k oldu\u011funda kullan\u0131l\u0131r. Yutma g\u00fc\u00e7l\u00fc\u011f\u00fcnde genellikle g\u00f6r\u00fcnt\u00fclemenin yan\u0131nda bir yutma testi de gerekir.<sup><a href=\"#ref-o5\">6<\/a>, <a href=\"#ref-o6\">7<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-spinal-segments-affected-by-dish\">DISH omurgan\u0131n hangi b\u00f6l\u00fcmlerini etkiler?<\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/04\/DISH-in-the-Thoracic-and-Cervical-Regions-11.jpeg\" alt=\"Boyun ve s\u0131rt b\u00f6l\u00fcmleri i\u015faretlenmi\u015f omurga \u00e7izimi\" class=\"wp-image-5249\"\/><figcaption class=\"wp-element-caption\">DISH en s\u0131k burada i\u015faretlenen torakal (s\u0131rt) ve servikal (boyun) b\u00f6l\u00fcmleri etkiler. Bel omurgas\u0131 ve omurga d\u0131\u015f\u0131ndaki b\u00f6lgeler de etkilenebilir.<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-in-the-thoracic-spine\">Torakal omurga<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DISH&#8217;in en s\u0131k g\u00f6r\u00fcld\u00fc\u011f\u00fc yer torakal omurgad\u0131r, \u00f6zellikle orta ve alt seviyeleri. Klasik tabloda osteofitler omurlar\u0131n sa\u011f taraf\u0131nda b\u00fcy\u00fcr, inen aort ise solda seyreder. 101 hastan\u0131n BT&#8217;sini inceleyen bir \u00e7al\u0131\u015fma bunun nas\u0131l de\u011fi\u015fti\u011fini izledi. T5&#8217;ten T10&#8217;a kadar osteofitler \u00e7o\u011funlukla sa\u011fdayd\u0131. Daha a\u015fa\u011f\u0131da, aort omurgan\u0131n ortas\u0131na do\u011fru kayd\u0131k\u00e7a, osteofitler iki tarafta da olu\u015ftu; aortun yan\u0131nda kalanlar daha yass\u0131yd\u0131 ya da aortun \u00e7evresinde k\u0131vr\u0131l\u0131yordu. \u00c7al\u0131\u015fma bu ili\u015fkiyi tarif ediyor, ama aortun kemik olu\u015fumunu nas\u0131l etkiledi\u011fini kan\u0131tlam\u0131yor.<sup><a href=\"#ref-o9\">10<\/a><\/sup><\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-19-at-7.22.49&#x202F;PM.png\" alt=\"Alt torakal omurun kesitsel BT g\u00f6r\u00fcnt\u00fcs\u00fc: hastan\u0131n sa\u011f\u0131nda bir osteofit, solda daire i\u00e7ine al\u0131nm\u0131\u015f aort\" class=\"wp-image-5554\" style=\"width:618px;height:auto\"\/><figcaption class=\"wp-element-caption\">Kesitsel g\u00f6r\u00fcnt\u00fcde alt torakal seviye. Beyaz ok hastan\u0131n sa\u011f\u0131ndaki osteofiti, daire soldaki aortu g\u00f6steriyor. Bu t\u00fcr b\u00fct\u00fcn g\u00f6r\u00fcnt\u00fclerde oldu\u011fu gibi hastan\u0131n sa\u011f\u0131 resmin solunda yer al\u0131r.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-19-at-7.17.05&#x202F;PM-1024x1013.png\" alt=\"Torakolomber bile\u015fkede kesitsel BT g\u00f6r\u00fcnt\u00fcs\u00fc: omurun iki yan\u0131nda osteofitler, \u00f6nde aort\" class=\"wp-image-5559\" style=\"width:670px;height:auto\"\/><figcaption class=\"wp-element-caption\">S\u0131rt ve bel omurgas\u0131n\u0131n birle\u015fti\u011fi yerde aort (kesikli daire) ortaya daha yak\u0131nd\u0131r ve osteofitler (beyaz oklar) iki tarafta da olu\u015fur. Sar\u0131 \u00e7izgi aortun yan\u0131ndaki, bu hastada kemik bulunmayan alan\u0131 g\u00f6steriyor.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Kom\u015fu osteofitler b\u00fcy\u00fcd\u00fck\u00e7e baz\u0131lar\u0131 birle\u015ferek akan, dalgal\u0131 hatl\u0131 kesintisiz bir k\u00f6pr\u00fc olu\u015fturur. Baz\u0131lar\u0131 ise ayr\u0131 kal\u0131r ve sivri bir &#8220;ku\u015f gagas\u0131&#8221; bi\u00e7imi al\u0131r. Bu k\u00f6pr\u00fcler, zaten boyun ve belden daha az hareket eden torakal omurgay\u0131 daha da sertle\u015ftirir.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-18-at-6.11.24&#x202F;PM-847x1024.png\" alt=\"Torakal omurgan\u0131n yandan BT g\u00f6r\u00fcnt\u00fcs\u00fc: birle\u015fmi\u015f dalgal\u0131 osteofitler ve ayr\u0131, gaga bi\u00e7imli osteofitler\" class=\"wp-image-5527\" style=\"width:572px;height:auto\"\/><figcaption class=\"wp-element-caption\">DISH&#8217;te torakal osteofitler. Baz\u0131lar\u0131 dalgal\u0131 bir k\u00f6pr\u00fcde birle\u015fmi\u015f, baz\u0131lar\u0131 ayr\u0131 kalm\u0131\u015f ve ku\u015f gagas\u0131 bi\u00e7iminde.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Bu osteofitlerin yak\u0131n\u0131ndan sinirler ge\u00e7er. \u0130\u00e7 organlar\u0131n \u00e7al\u0131\u015fmas\u0131n\u0131 d\u00fczenlemeye katk\u0131da bulunan sempatik sinir dallar\u0131 torakal omurlar\u0131n \u00f6n ve yan y\u00fcz\u00fcn\u00fc \u00e7aprazlar. Kadavralar \u00fczerinde yap\u0131lan geni\u015f bir \u00e7al\u0131\u015fmada, incelenen omurgalar\u0131n yakla\u015f\u0131k \u00fc\u00e7te ikisinde osteofitlerin bu dallara bask\u0131 yapt\u0131\u011f\u0131 bulundu. Yay\u0131mlanm\u0131\u015f bir olguda, b\u00f6yle bir sinire bask\u0131 yapan osteofit al\u0131nd\u0131ktan sonra hastan\u0131n s\u0131rt ortas\u0131 ve \u00fcst kar\u0131n a\u011fr\u0131s\u0131 azald\u0131. Bu anatomi, baz\u0131 torakal \u015fik\u00e2yetlerin neden ara\u015ft\u0131r\u0131lmaya de\u011fer oldu\u011funu a\u00e7\u0131klar. DISH&#8217;in s\u0131k olarak kalp ya da sindirim sorunlar\u0131na yol a\u00e7t\u0131\u011f\u0131n\u0131 ise g\u00f6stermez.<sup><a href=\"#ref-o10\">11<\/a>, <a href=\"#ref-o11\">12<\/a><\/sup> Tedavi yaz\u0131s\u0131nda <a href=\"https:\/\/kamranaghayev.com\/tr\/dish-hastaligi-tedavisi\/#h-thoracic-osteophytes-and-sympathetic-nerves\">torasik osteofitlerin de\u011ferlendirilmesi<\/a> ve kan\u0131tlar\u0131n s\u0131n\u0131rlar\u0131 anlat\u0131l\u0131yor.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-sert-bir-b-l-m-neden-nemlidir\">Sert bir b\u00f6l\u00fcm neden \u00f6nemlidir?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Birka\u00e7 omur kayna\u015ft\u0131\u011f\u0131nda \u00fcstteki ve alttaki seviyeler hareketin ve y\u00fck\u00fcn daha b\u00fcy\u00fck b\u00f6l\u00fcm\u00fcn\u00fc \u00fcstlenir. DISH bu seviyelerde s\u0131kl\u0131kla disk dejenerasyonu ve kanal darl\u0131\u011f\u0131yla birlikte g\u00f6r\u00fcl\u00fcr; bunlar sinirlere ya da omurili\u011fe bask\u0131 yapabilir ve kendi ba\u015flar\u0131na tedavi gerektirir. Uzun bir kayna\u015fm\u0131\u015f b\u00f6l\u00fcm ayn\u0131 zamanda kald\u0131ra\u00e7 gibi davran\u0131r; esnek bir omurgada yaln\u0131zca morluk b\u0131rakacak bir d\u00fc\u015fme, sert bir omurgay\u0131 k\u0131rabilir.<sup><a href=\"#ref-o2\">2<\/a>, <a href=\"#ref-o12\">13<\/a><\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-in-the-cervical-spine\">Servikal (boyun) omurga<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Boyunda osteofitler omurlar\u0131n \u00f6n y\u00fcz\u00fcnde b\u00fcy\u00fcr ve genellikle torakal omurgadakinden daha simetriktir. Ola\u011fan belirtiler boyun a\u011fr\u0131s\u0131, tutukluk ve hareket k\u0131s\u0131tl\u0131l\u0131\u011f\u0131d\u0131r. B\u00fcy\u00fck osteofitler yemek borusuna bask\u0131 yaparak yutma g\u00fc\u00e7l\u00fc\u011f\u00fcne, nadiren de hava yoluna bask\u0131ya yol a\u00e7abilir.<sup><a href=\"#ref-o5\">6<\/a><\/sup> Torakal omurgada oldu\u011fu gibi, kayna\u015fm\u0131\u015f b\u00f6l\u00fcm\u00fcn kom\u015fu seviyeleri y\u0131pranabilir ve omurili\u011fe ya da sinir k\u00f6klerine bask\u0131 yaparak kollarda veya bacaklarda uyu\u015fmaya, g\u00fc\u00e7s\u00fczl\u00fc\u011fe ya da dengesiz y\u00fcr\u00fcmeye neden olabilir.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-in-the-lumbar-spine\">Lomber (bel) omurga<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DISH bel b\u00f6lgesine daha seyrek ula\u015f\u0131r. Buradaki osteofitler genellikle iki tarafta olu\u015fur ve DISH s\u0131kl\u0131kla bel kanal\u0131 darl\u0131\u011f\u0131yla birlikte bulunur.<sup><a href=\"#ref-o9\">10<\/a><\/sup> Darl\u0131k ameliyat\u0131ndan \u00f6nce DISH&#8217;in fark edilmesi faydal\u0131d\u0131r: bel omurgas\u0131na uzanan DISH, yeniden ameliyat gerekme riskinin daha y\u00fcksek olmas\u0131yla ili\u015fkilendirilmi\u015ftir.<sup><a href=\"#ref-o13\">14<\/a><\/sup><\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-19-at-7.18.55&#x202F;PM-710x1024.png\" alt=\"Bel omurgas\u0131n\u0131n yandan BT g\u00f6r\u00fcnt\u00fcs\u00fc: L2 ile L3 aras\u0131nda gaga bi\u00e7imli bir osteofit ve L4'ten sakruma uzanan b\u00fcy\u00fck bir f\u00fczyon kitlesi\" class=\"wp-image-5564\" style=\"width:520px;height:auto\"\/><figcaption class=\"wp-element-caption\">Bel omurgas\u0131nda DISH. Beyaz ok L2 ile L3 aras\u0131ndaki gaga bi\u00e7imli osteofiti g\u00f6steriyor. Arkada L4&#8217;ten sakruma uzanan b\u00fcy\u00fck kemik kitlesi \u00f6nceki ameliyatlardan kalan f\u00fczyondur; bu hastan\u0131n alt bel omurgas\u0131 daha \u00f6nce birka\u00e7 kez ameliyat edilmi\u015fti.<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-extraspinal-dish\">Omurga d\u0131\u015f\u0131nda<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DISH le\u011fen kemi\u011fi \u00e7evresindeki, topuk, diz, dirsek ve eldeki ba\u011f ve tendon yap\u0131\u015fma yerlerini de etkileyebilir. Bu de\u011fi\u015fiklikler \u00e7o\u011fu zaman az \u015fik\u00e2yete yol a\u00e7ar, ama baz\u0131 yap\u0131\u015fma yerleri a\u011fr\u0131l\u0131 h\u00e2le gelebilir. Ellerdeki kemik b\u00fcy\u00fcmesi osteoartriti and\u0131rabilir ve iki durum s\u0131kl\u0131kla birlikte g\u00f6r\u00fcl\u00fcr.<sup><a href=\"#ref-o14\">4<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dish-and-related-conditions\">DISH, ankilozan spondilit ve dejenerasyon<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-vs-ankylosing-spondylitis\">DISH mi, ankilozan spondilit mi?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0130ki hastal\u0131k da omurgan\u0131n kayna\u015fmas\u0131na yol a\u00e7abilir. Ankilozan spondilit aksiyel spondiloartrit grubundand\u0131r: genellikle gen\u00e7 eri\u015fkinlerde ba\u015flayan, tipik olarak iltihabi bel a\u011fr\u0131s\u0131 ve sakroiliak eklem tutulumuyla seyreden iltihabi bir hastal\u0131kt\u0131r. DISH ise genellikle daha ileri ya\u015fta tan\u0131 al\u0131r ve \u00e7o\u011funlukla iltihabi olmayan bir durum olarak s\u0131n\u0131flan\u0131r; DISH&#8217;te kemik olu\u015fumunun biyolojisi ise ara\u015ft\u0131r\u0131lmaya devam ediyor. G\u00f6r\u00fcnt\u00fclerdeki tablolar ortalamada farkl\u0131d\u0131r, ama k\u0131smen \u00f6rt\u00fc\u015f\u00fcr.<sup><a href=\"#ref-o2\">2<\/a>, <a href=\"#ref-o7\">8<\/a><\/sup><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th><\/th><th>Tipik DISH<\/th><th>Tipik ankilozan spondilit<\/th><\/tr><\/thead><tbody><tr><td>Tan\u0131daki ola\u011fan ya\u015f<\/td><td>\u0130leri ya\u015ftaki eri\u015fkinler<\/td><td>Gen\u00e7 eri\u015fkinler<\/td><\/tr><tr><td>Hastal\u0131\u011f\u0131n niteli\u011fi<\/td><td>Yap\u0131\u015fma yerlerinde, \u00e7o\u011funlukla iltihabi olmayan kemik olu\u015fumu<\/td><td>Omurga ve sakroiliak eklemlerin iltihabi hastal\u0131\u011f\u0131<\/td><\/tr><tr><td>Omurgan\u0131n \u00f6n\u00fcndeki k\u00f6pr\u00fcler<\/td><td>Kal\u0131n, akan, &#8220;erimi\u015f mum&#8221; g\u00f6r\u00fcn\u00fcml\u00fc kemik<\/td><td>\u0130nce, d\u00fczg\u00fcn k\u00f6pr\u00fcler<\/td><\/tr><tr><td>Sakroiliak eklemler<\/td><td>Eklemler \u00e7evresinde k\u00f6pr\u00fcle\u015fme s\u0131k; baz\u0131 ki\u015filerde k\u0131smi kayna\u015fma olur<\/td><td>Tam kayna\u015fma daha tipiktir<\/td><\/tr><tr><td>Faset eklemler<\/td><td>Kayna\u015fma seyrek<\/td><td>Kayna\u015fma daha s\u0131k<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Kaynaklar: DISH&#8217;li 111 ve ankilozan spondilitli 27 ki\u015fiyi kar\u015f\u0131la\u015ft\u0131ran BT \u00e7al\u0131\u015fmas\u0131;<sup><a href=\"#ref-o7\">8<\/a><\/sup> klinik derleme.<sup><a href=\"#ref-o2\">2<\/a><\/sup> Bu \u00e7al\u0131\u015fmada DISH hastalar\u0131n\u0131n %63&#8217;\u00fcnde sakroiliak eklemde k\u0131smi ya da tam kayna\u015fma vard\u0131; %11&#8217;inde ise ankilozan spondilite daha \u00f6zg\u00fc d\u00fczg\u00fcn k\u00f6pr\u00fcler g\u00f6r\u00fcld\u00fc. Bu y\u00fczden doktorlar tek bir bulguya de\u011fil, tablonun b\u00fct\u00fcn\u00fcne bakar.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/kamranaghayev.com\/wp-content\/uploads\/2024\/04\/DISH-vs-Ankylosing-Spondylitis-11.jpeg\" alt=\"Sa\u011fl\u0131kl\u0131 omurga ile ankilozan spondilitte iltihaplanm\u0131\u015f ve kayna\u015fm\u0131\u015f omurgan\u0131n kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131 \u00e7izim\" class=\"wp-image-5257\"\/><figcaption class=\"wp-element-caption\">Ankilozan spondilit: sa\u011fl\u0131kl\u0131 bir omurgan\u0131n yan\u0131nda omurga eklemlerinin iltihab\u0131 ve kayna\u015fmas\u0131. \u00c7izim DISH&#8217;i g\u00f6stermiyor.<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-disc-degeneration\">DISH mi, disk dejenerasyonu mu?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Disk dejenerasyonu ya\u015fla \u00e7ok yayg\u0131nla\u015f\u0131r ve o da osteofit olu\u015fturur. Dejenerasyonda disk aral\u0131\u011f\u0131 daral\u0131r ve osteofitler etkilenen disklerin \u00e7evresinde, en s\u0131k boyunda ve belde bulunur. Klasik DISH&#8217;te disk aral\u0131klar\u0131 g\u00f6rece korunur ve kemik birka\u00e7 seviye boyunca kesintisiz akar; en s\u0131k da torakal omurgada.<sup><a href=\"#ref-o1\">1<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0130ki durum s\u0131kl\u0131kla bir arada bulunur ve DISH kayna\u015fm\u0131\u015f b\u00f6l\u00fcm\u00fcn kom\u015fu seviyelerindeki y\u00fck\u00fc art\u0131rabilir. G\u00f6r\u00fcnt\u00fcde DISH bulunmas\u0131, a\u011fr\u0131n\u0131n ya da sinir bas\u0131s\u0131n\u0131n ayr\u0131 bir dejeneratif nedeni olmad\u0131\u011f\u0131 anlam\u0131na gelmez.<sup><a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-diffuse-idiopathic-skeletal-hyperostosis-causes\">Nedenleri ve ili\u015fkili durumlar<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">DISH&#8217;in nedeni tam olarak anla\u015f\u0131lm\u0131\u015f de\u011fildir. En belirgin risk etkenleri ya\u015f ve erkek cinsiyettir. DISH ayr\u0131ca obezite, tip 2 diyabet, y\u00fcksek tansiyon ve kan ya\u011flar\u0131ndaki bozukluklarla ili\u015fkilidir. Bu durumlar\u0131n DISH&#8217;e katk\u0131da m\u0131 bulundu\u011fu, yoksa ortak nedenleri mi payla\u015ft\u0131klar\u0131 hen\u00fcz bilinmiyor.<sup><a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ara\u015ft\u0131rmac\u0131lar genleri ve normalde yumu\u015fak dokular\u0131n kire\u00e7lenmesini \u00f6nleyen kimyay\u0131 inceliyor. Bu \u00e7al\u0131\u015fmalardan biri, kire\u00e7lenmenin do\u011fal bir freni olan pirofosfat\u0131 \u00fcreten ENPP1 enzimiyle ilgili. ENPP1 genindeki de\u011fi\u015fiklikler, DISH ve erken ba\u015flang\u0131\u00e7l\u0131 osteoporozu olan az say\u0131da ki\u015fide bulunmu\u015ftur.<sup><a href=\"#ref-o15\">15<\/a><\/sup> Bu, DISH&#8217;in genellikle kal\u0131tsal oldu\u011fu anlam\u0131na gelmez ve DISH i\u00e7in rutin bir genetik test yoktur. Bu ara\u015ft\u0131rmalar\u0131n tedavi a\u00e7\u0131s\u0131ndan ne anlama gelebilece\u011fi, tedavi yaz\u0131s\u0131ndaki <a href=\"https:\/\/kamranaghayev.com\/tr\/dish-hastaligi-tedavisi\/#h-is-there-a-new-treatment-for-dish\">&#8220;DISH i\u00e7in yeni bir tedavi var m\u0131?&#8221;<\/a> b\u00f6l\u00fcm\u00fcnde anlat\u0131l\u0131yor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dish-prognosis\">Seyir ve tedavi<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-how-fast-does-dish-disease-progress\">DISH ne kadar h\u0131zl\u0131 ilerler?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DISH yava\u015f, genellikle y\u0131llar i\u00e7inde geli\u015fir. Pek \u00e7ok ki\u015fide tutukluk ve a\u011fr\u0131 uzun s\u00fcre katlan\u0131labilir d\u00fczeyde kal\u0131r; baz\u0131lar\u0131nda ise hareket giderek daha \u00e7ok k\u0131s\u0131tlan\u0131r. G\u00f6r\u00fcnt\u00fclerdeki de\u011fi\u015fikliklerle \u015fik\u00e2yetler her zaman birlikte ilerlemez ve bir ki\u015finin seyrini \u00f6ng\u00f6rmenin g\u00fcvenilir bir yolu yoktur. Takip sabit bir takvime g\u00f6re de\u011fil, \u015fik\u00e2yetlerinize ve varsa komplikasyonlara g\u00f6re planlanmal\u0131d\u0131r.<sup><a href=\"#ref-o2\">2<\/a><\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-ya-am-s-resini-etkiler-mi\">DISH ya\u015fam s\u00fcresini etkiler mi?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DISH tek ba\u015f\u0131na ki\u015fisel bir ya\u015fam s\u00fcresi tahmini vermez. Daha \u00f6nemli olan, ba\u015fta d\u00fc\u015fme sonras\u0131 k\u0131r\u0131klar olmak \u00fczere komplikasyonlar\u0131 ve DISH&#8217;le ili\u015fkili sa\u011fl\u0131k sorunlar\u0131d\u0131r. DISH&#8217;li ki\u015filerde ortalamada koroner arter hastal\u0131\u011f\u0131 daha s\u0131k g\u00f6r\u00fcl\u00fcr; bu bir ili\u015fkidir ve kemik b\u00fcy\u00fcmesinin kalbe zarar verdi\u011finin kan\u0131t\u0131 de\u011fil, kalp sa\u011fl\u0131\u011f\u0131na dikkat etmek i\u00e7in bir nedendir.<sup><a href=\"#ref-o6\">7<\/a>, <a href=\"#ref-o16\">16<\/a><\/sup><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-is-dish-disease-a-disability\">DISH engellilik say\u0131l\u0131r m\u0131?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">DISH baz\u0131 ki\u015filerde hareketi ve g\u00fcnl\u00fck ya\u015fam\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde k\u0131s\u0131tlayabilir. Bunun engellilik olarak kabul edilip edilmeyece\u011fi belgelenmi\u015f k\u0131s\u0131tl\u0131l\u0131klara ve ilgili \u00fclkenin ya da kurumun kurallar\u0131na ba\u011fl\u0131d\u0131r. Tan\u0131 tek ba\u015f\u0131na bu soruyu yan\u0131tlamaz.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dish-treatment-summary\">DISH nas\u0131l tedavi edilir?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Tedavi DISH&#8217;in yol a\u00e7t\u0131\u011f\u0131 soruna y\u00f6neliktir. Tutukluk ve a\u011fr\u0131 genellikle egzersiz, fizik tedavi ve uygun a\u011fr\u0131 tedavisiyle y\u00f6netilir. Ameliyat belirli sorunlar i\u00e7in d\u00fc\u015f\u00fcn\u00fcl\u00fcr: yutmay\u0131 engelleyen boyun osteofitleri, omurilik ya da sinir bas\u0131s\u0131, dengesiz bir k\u0131r\u0131k ve se\u00e7ilmi\u015f durumlarda yak\u0131ndaki yap\u0131lara bask\u0131 yapan torasik osteofitler. DISH tan\u0131s\u0131 tek ba\u015f\u0131na ameliyat nedeni de\u011fildir. <a href=\"https:\/\/kamranaghayev.com\/tr\/dish-hastaligi-tedavisi\/\">DISH hastal\u0131\u011f\u0131 tedavisi<\/a> yaz\u0131s\u0131 her se\u00e7ene\u011fi, ameliyat\u0131n neyi yap\u0131p neyi yapamayaca\u011f\u0131n\u0131 ve de\u011ferlendirmenin nas\u0131l i\u015fledi\u011fini anlat\u0131yor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u015eik\u00e2yetler hayat\u0131n\u0131z\u0131 k\u0131s\u0131tl\u0131yorsa, tan\u0131 net de\u011filse ya da bir g\u00f6r\u00fcnt\u00fc komplikasyona i\u015faret ediyorsa, bir uzman g\u00f6r\u00fc\u015f\u00fc yard\u0131mc\u0131 olabilir. Do\u00e7. Dr. Kamran Aghayev ile <a href=\"https:\/\/kamranaghayev.com\/tr\/online-danismanlik\/\">online dan\u0131\u015fmanl\u0131k talep edebilir<\/a> ya da <a href=\"https:\/\/kamranaghayev.com\/tr\/randevu-al\/\">\u0130stanbul&#8217;da randevu alabilir<\/a>, <a href=\"https:\/\/kamranaghayev.com\/tr\/hakkimda\/\">Do\u00e7. Dr. Aghayev&#8217;in \u00f6zge\u00e7mi\u015fi ve yay\u0131nlar\u0131<\/a> hakk\u0131nda bilgi edinebilirsiniz.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-references\">Kaynaklar<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o1\">1. <a href=\"https:\/\/doi.org\/10.1148\/119.3.559\" target=\"_blank\" rel=\"noreferrer noopener\">Resnick and Niwayama. Radiographic and pathologic features of spinal involvement in diffuse idiopathic skeletal hyperostosis (DISH)<\/a>. Radiology, 1976. Original imaging and pathology study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o2\">2. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34559699\/\" target=\"_blank\" rel=\"noreferrer noopener\">Le et al. Diffuse idiopathic skeletal hyperostosis of the spine: pathophysiology, diagnosis, and management<\/a>. Journal of the American Academy of Orthopaedic Surgeons, 2021. Clinical review.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o3\">3. <a href=\"https:\/\/doi.org\/10.1136\/ard.9.4.321\" target=\"_blank\" rel=\"noreferrer noopener\">Forestier and Rotes-Querol. Senile ankylosing hyperostosis of the spine<\/a>. Annals of the Rheumatic Diseases, 1950. Original description.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o14\">4. <a href=\"https:\/\/doi.org\/10.1148\/15.3.513\" target=\"_blank\" rel=\"noreferrer noopener\">Resnick et al. Diffuse idiopathic skeletal hyperostosis (DISH): Forestier&#8217;s disease with extraspinal manifestations<\/a>. Radiology, 1975. Original description of changes outside the spine.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o4\">5. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41963077\/\" target=\"_blank\" rel=\"noreferrer noopener\">Kiefer et al. Spinal mobility and functional limitations in patients with diffuse idiopathic skeletal hyperostosis compared with axial spondyloarthritis and healthy controls<\/a>. RMD Open, 2026. Observational comparison of 50 people with DISH, 30 with axial spondyloarthritis and 20 healthy controls.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o5\">6. <a href=\"https:\/\/doi.org\/10.1016\/j.spinee.2022.03.002\" target=\"_blank\" rel=\"noreferrer noopener\">Harlianto et al. Diffuse idiopathic skeletal hyperostosis of the cervical spine causing dysphagia and airway obstruction: an updated systematic review<\/a>. The Spine Journal, 2022. Systematic review.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o6\">7. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30210963\/\" target=\"_blank\" rel=\"noreferrer noopener\">Reinhold et al. Spine fractures in ankylosing diseases: recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)<\/a>. Global Spine Journal, 2018. Specialist recommendations.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o7\">8. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36725891\/\" target=\"_blank\" rel=\"noreferrer noopener\">Takahashi et al. Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis using whole-spine CT<\/a>. Scientific Reports, 2023. Comparative CT study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o8\">9. <a href=\"https:\/\/doi.org\/10.1007\/s00330-016-4355-x\" target=\"_blank\" rel=\"noreferrer noopener\">Oudkerk et al. Diagnosis of diffuse idiopathic skeletal hyperostosis with chest computed tomography: inter-observer agreement<\/a>. European Radiology, 2017. CT criteria study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o9\">10. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37680188\/\" target=\"_blank\" rel=\"noreferrer noopener\">Chen et al. Not all osteophytes are located on the right side of the vertebrae in diffuse idiopathic skeletal hyperostosis: a quantitative analysis in relation to the position of aorta<\/a>. Orthopaedic Surgery, 2023. Retrospective CT study of 101 patients.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o10\">11. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3660077\/\" target=\"_blank\" rel=\"noreferrer noopener\">Nathan. Osteophytes of the spine compressing the sympathetic trunk and splanchnic nerves in the thorax<\/a>. Spine, 1987. Cadaver study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o11\">12. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33771615\/\" target=\"_blank\" rel=\"noreferrer noopener\">Jankowski et al. Thoracic osteophyte as a cause of symptomatic greater splanchnic nerve compression. Case report<\/a>. Neurochirurgie, 2022; online 2021. Single case.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o12\">13. <a href=\"https:\/\/doi.org\/10.1097\/BRS.0000000000003151\" target=\"_blank\" rel=\"noreferrer noopener\">Murakami et al. Association between vertebral fracture and diffuse idiopathic skeletal hyperostosis<\/a>. Spine, 2019. Retrospective study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o13\">14. <a href=\"https:\/\/doi.org\/10.1097\/BRS.0000000000002618\" target=\"_blank\" rel=\"noreferrer noopener\">Yamada et al. Diffuse idiopathic skeletal hyperostosis extended to the lumbar segment is a risk factor of reoperation in patients treated surgically for lumbar stenosis<\/a>. Spine, 2018. Retrospective surgical study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o15\">15. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35340077\/\" target=\"_blank\" rel=\"noreferrer noopener\">Kato et al. Identification of ENPP1 haploinsufficiency in patients with diffuse idiopathic skeletal hyperostosis and early-onset osteoporosis<\/a>. Journal of Bone and Mineral Research, 2022. Small genetic case series.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"ref-o16\">16. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31181416\/\" target=\"_blank\" rel=\"noreferrer noopener\">Oudkerk et al. Subjects with diffuse idiopathic skeletal hyperostosis have an increased burden of coronary artery disease: an evaluation in the COPDGene cohort<\/a>. Atherosclerosis, 2019. Observational association.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DISH (Forestier hastal\u0131\u011f\u0131): omurga boyunca neden kemik olu\u015fur, r\u00f6ntgen ve BT neler g\u00f6sterir, ankilozan spondilitten fark\u0131 nedir ve ne zaman doktora ba\u015fvurmal\u0131.<\/p>\n","protected":false},"author":2,"featured_media":4037,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","ka_reviewed_on":"","ka_updated_on":"","footnotes":""},"categories":[24,31],"tags":[],"class_list":["post-2992","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hastaliklar","category-omurga-hastaliklari"],"acf":[],"_links":{"self":[{"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/posts\/2992","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/comments?post=2992"}],"version-history":[{"count":3,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/posts\/2992\/revisions"}],"predecessor-version":[{"id":7498,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/posts\/2992\/revisions\/7498"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/media\/4037"}],"wp:attachment":[{"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/media?parent=2992"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/categories?post=2992"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kamranaghayev.com\/tr\/wp-json\/wp\/v2\/tags?post=2992"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}